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Literature summary extracted from

  • Huang, K.; Gao, L.; Yang, M.; Wang, J.; Wang, Z.; Wang, L.; Wang, G.; Li, H.
    Exogenous cathepsin V protein protects human cardiomyocytes HCM from angiotensin II-induced hypertrophy (2017), Int. J. Biochem. Cell Biol., 89, 6-15 .
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
3.4.22.43 additional information CTSV knockdown by RNAi Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.43 Homo sapiens O60911
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.43 cardiomyocyte
-
 Homo sapiens
-
3.4.22.43 HCM cell
-
 Homo sapiens
-
3.4.22.43 heart
-
 Homo sapiens
-
3.4.22.43 myocardium
-
 Homo sapiens
-

Synonyms

EC Number Synonyms Comment Organism
3.4.22.43 CTSV
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
3.4.22.43 physiological function exogenous cathepsin V protein protects human cardiomyocytes from angiotensin II-induced hypertrophy, human cardiomyocytes hypertrophic cardiomyopathy (HCM) as a cell model to investigate the effects of exogenous CTSV on Ang II-induced cardiac cell hypertrophy, overview. Analysis of the mechanism of CTSV cardioprotection, overview. Exogenous CTSV inhibits Ang II-induced hypertrophy in HCM cells by inhibiting PI3K/Akt/mTOR Homo sapiens